Chronic intermittent hypoxia increases rat sternohyoid muscle NADPH oxidase expression with attendant modest oxidative stress

Chronic intermittent hypoxia (CIH) causes upper airway muscle dysfunction. We hypothesized that the superoxide generating NADPH oxidase (NOX) is upregulated in CIH-exposed muscle causing oxidative stress. Adult male Wistar rats were exposed to intermittent hypoxia (5% O(2) at the nadir for 90 s foll...

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Detalles Bibliográficos
Autores principales: Williams, Robert, Lemaire, Paul, Lewis, Philip, McDonald, Fiona B., Lucking, Eric, Hogan, Sean, Sheehan, David, Healy, Vincent, O'Halloran, Ken D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311627/
https://www.ncbi.nlm.nih.gov/pubmed/25688214
http://dx.doi.org/10.3389/fphys.2015.00015

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