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Enantioselective synthesis of polyhydroxyindolizidinone and quinolizidinone derivatives from a common precursor

A concise asymmetric synthetic route to two new tetrahydroxyindolizidinone and quinolizidinone derivatives has been developed from a common intermediate which featured a highly selective dihydroxylation reaction and a RCM reaction as key steps.

Detalles Bibliográficos
Autores principales: Saha, Nemai, Chattopadhyay, Shital K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311665/
https://www.ncbi.nlm.nih.gov/pubmed/25670979
http://dx.doi.org/10.3762/bjoc.10.327
Descripción
Sumario:A concise asymmetric synthetic route to two new tetrahydroxyindolizidinone and quinolizidinone derivatives has been developed from a common intermediate which featured a highly selective dihydroxylation reaction and a RCM reaction as key steps.