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Aspergillus Flavus Endocarditis of the Native Mitral Valve in a Bone Marrow Transplant Patient

Patient: Male, 36 Final Diagnosis: Aspergillus flavus endocarditis Symptoms: Malaise • fatigue and dyspnea Medication: — Clinical Procedure: Mitral vale replacemnet Specialty: Cardiology OBJECTIVE: Rare disease BACKGROUND: Infective endocarditis due to Aspergillus species is an uncommon infection wi...

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Autores principales: Demir, Tolga, Ergenoglu, Mehmet Umit, Ekinci, Abdurrahman, Tanrikulu, Nursen, Sahin, Mazlum, Demirsoy, Ergun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311906/
https://www.ncbi.nlm.nih.gov/pubmed/25603977
http://dx.doi.org/10.12659/AJCR.892428
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author Demir, Tolga
Ergenoglu, Mehmet Umit
Ekinci, Abdurrahman
Tanrikulu, Nursen
Sahin, Mazlum
Demirsoy, Ergun
author_facet Demir, Tolga
Ergenoglu, Mehmet Umit
Ekinci, Abdurrahman
Tanrikulu, Nursen
Sahin, Mazlum
Demirsoy, Ergun
author_sort Demir, Tolga
collection PubMed
description Patient: Male, 36 Final Diagnosis: Aspergillus flavus endocarditis Symptoms: Malaise • fatigue and dyspnea Medication: — Clinical Procedure: Mitral vale replacemnet Specialty: Cardiology OBJECTIVE: Rare disease BACKGROUND: Infective endocarditis due to Aspergillus species is an uncommon infection with a high mortality rate. It mostly occurs after the implantation of prosthetic heart valves. Parenteral nutrition, immunosuppression, broad-spectrum antibiotic regimens, and illegal intravenous drug use are the risk factors for developing infection. CASE REPORT: We report a case of Aspergillus flavus native mitral valve endocarditis in a patient who had allogeneic stem cell transplantation in the past due to myelodysplastic syndrome. CONCLUSIONS: Although it is rare and there is limited experience available with the diagnosis and treatment, early recognition and therapeutic intervention with systemic antifungal therapy and aggressive surgical intervention are critical to prevent further complications that may eventually lead to death. In addition, better novel diagnostic tools are needed to facilitate more accurate identification of patients with invasive Aspergillus and to permit earlier initiation of antifungal treatment.
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spelling pubmed-43119062015-02-02 Aspergillus Flavus Endocarditis of the Native Mitral Valve in a Bone Marrow Transplant Patient Demir, Tolga Ergenoglu, Mehmet Umit Ekinci, Abdurrahman Tanrikulu, Nursen Sahin, Mazlum Demirsoy, Ergun Am J Case Rep Articles Patient: Male, 36 Final Diagnosis: Aspergillus flavus endocarditis Symptoms: Malaise • fatigue and dyspnea Medication: — Clinical Procedure: Mitral vale replacemnet Specialty: Cardiology OBJECTIVE: Rare disease BACKGROUND: Infective endocarditis due to Aspergillus species is an uncommon infection with a high mortality rate. It mostly occurs after the implantation of prosthetic heart valves. Parenteral nutrition, immunosuppression, broad-spectrum antibiotic regimens, and illegal intravenous drug use are the risk factors for developing infection. CASE REPORT: We report a case of Aspergillus flavus native mitral valve endocarditis in a patient who had allogeneic stem cell transplantation in the past due to myelodysplastic syndrome. CONCLUSIONS: Although it is rare and there is limited experience available with the diagnosis and treatment, early recognition and therapeutic intervention with systemic antifungal therapy and aggressive surgical intervention are critical to prevent further complications that may eventually lead to death. In addition, better novel diagnostic tools are needed to facilitate more accurate identification of patients with invasive Aspergillus and to permit earlier initiation of antifungal treatment. International Scientific Literature, Inc. 2015-01-21 /pmc/articles/PMC4311906/ /pubmed/25603977 http://dx.doi.org/10.12659/AJCR.892428 Text en © Am J Case Rep, 2015 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License
spellingShingle Articles
Demir, Tolga
Ergenoglu, Mehmet Umit
Ekinci, Abdurrahman
Tanrikulu, Nursen
Sahin, Mazlum
Demirsoy, Ergun
Aspergillus Flavus Endocarditis of the Native Mitral Valve in a Bone Marrow Transplant Patient
title Aspergillus Flavus Endocarditis of the Native Mitral Valve in a Bone Marrow Transplant Patient
title_full Aspergillus Flavus Endocarditis of the Native Mitral Valve in a Bone Marrow Transplant Patient
title_fullStr Aspergillus Flavus Endocarditis of the Native Mitral Valve in a Bone Marrow Transplant Patient
title_full_unstemmed Aspergillus Flavus Endocarditis of the Native Mitral Valve in a Bone Marrow Transplant Patient
title_short Aspergillus Flavus Endocarditis of the Native Mitral Valve in a Bone Marrow Transplant Patient
title_sort aspergillus flavus endocarditis of the native mitral valve in a bone marrow transplant patient
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311906/
https://www.ncbi.nlm.nih.gov/pubmed/25603977
http://dx.doi.org/10.12659/AJCR.892428
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