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Therapy with Plasma Purified Alpha1-Antitrypsin (Prolastin(®)) Induces Time-Dependent Changes in Plasma Levels of MMP-9 and MPO

The common Z mutation (Glu342Lys) of α1-antitrypsin (A1AT) results in the polymerization and intracellular retention of A1AT protein. The concomitant deficiency of functional A1AT predisposes PiZZ subjects to early onset emphysema. Clinical studies have implied that, among the biomarkers associated...

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Detalles Bibliográficos
Autores principales:	Koepke, Janine, Dresel, Marc, Schmid, Severin, Greulich, Timm, Beutel, Björn, Schmeck, Bernd, Vogelmeier, Claus Franz, Janciauskiene, Sabina, Koczulla, Andreas Rembert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311911/ https://www.ncbi.nlm.nih.gov/pubmed/25635861 http://dx.doi.org/10.1371/journal.pone.0117497

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