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Efficient Uptake and Dissemination of Scrapie Prion Protein by Astrocytes and Fibroblasts from Adult Hamster Brain

Prion infections target neurons and lead to neuronal loss. However, the role of non-neuronal cells in the initiation and spread of infection throughout the brain remains unclear despite the fact these cells can also propagate prion infectivity. To evaluate how different brain cells process scrapie p...

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Detalles Bibliográficos
Autores principales: Hollister, Jason R., Lee, Kil Sun, Dorward, David W., Baron, Gerald S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311963/
https://www.ncbi.nlm.nih.gov/pubmed/25635871
http://dx.doi.org/10.1371/journal.pone.0115351

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