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Identification and Validation of a Linear Protective Neutralizing Epitope in the β-Pore Domain of Alpha Toxin
The plethora of virulence factors associated with Staphylococcus aureus make this bacterium an attractive candidate for a molecularly-designed epitope-focused vaccine. This approach, which necessitates the identification of neutralizing epitopes for incorporation into a vaccine construct, is being e...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311967/ https://www.ncbi.nlm.nih.gov/pubmed/25635901 http://dx.doi.org/10.1371/journal.pone.0116882 |