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Identification and Validation of a Linear Protective Neutralizing Epitope in the β-Pore Domain of Alpha Toxin

The plethora of virulence factors associated with Staphylococcus aureus make this bacterium an attractive candidate for a molecularly-designed epitope-focused vaccine. This approach, which necessitates the identification of neutralizing epitopes for incorporation into a vaccine construct, is being e...

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Detalles Bibliográficos
Autores principales: Oscherwitz, Jon, Cease, Kemp B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311967/
https://www.ncbi.nlm.nih.gov/pubmed/25635901
http://dx.doi.org/10.1371/journal.pone.0116882