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Lung Epithelial Cells Induce Both Phenotype Alteration and Senescence in Breast Cancer Cells

PURPOSE: The lung is one of the most common sites of breast cancer metastasis. While metastatic seeding is often accompanied by a dormancy-promoting mesenchymal to epithelial reverting transitions (MErT), we aimed to determine whether lung epithelial cells can impart this phenotype on aggressive bre...

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Detalles Bibliográficos
Autores principales: Furukawa, Masashi, Wheeler, Sarah, Clark, Amanda M., Wells, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311980/
https://www.ncbi.nlm.nih.gov/pubmed/25635394
http://dx.doi.org/10.1371/journal.pone.0118060