Cargando…

cAMP-induced actin cytoskeleton remodelling inhibits MKL1-dependent expression of the chemotactic and pro-proliferative factor, CCN1

Elevation of intracellular cAMP concentration has numerous vascular protective effects that are in part mediated via actin cytoskeleton-remodelling and subsequent regulation of gene expression. However, the mechanisms are incompletely understood. Here we investigated whether cAMP-induced actin-cytos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Duggirala, Aparna, Kimura, Tomomi E., Sala-Newby, Graciela B., Johnson, Jason L., Wu, Yih-Jer, Newby, Andrew C., Bond, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312355/ https://www.ncbi.nlm.nih.gov/pubmed/25446180 http://dx.doi.org/10.1016/j.yjmcc.2014.11.012

Ejemplares similares

Divergent Regulation of Actin Dynamics and Megakaryoblastic Leukemia-1 and -2 (Mkl1/2) by cAMP in Endothelial and Smooth Muscle Cells
por: Smith, Madeleine C., et al.
Publicado: (2017)

The Hippo pathway mediates inhibition of vascular smooth muscle cell proliferation by cAMP
por: Kimura, Tomomi E., et al.
Publicado: (2016)

Inhibition of Egr1 expression underlies the anti-mitogenic effects of cAMP in vascular smooth muscle cells
por: Kimura, Tomomi E., et al.
Publicado: (2014)

Dual Role of CREB in The Regulation of VSMC Proliferation: Mode of Activation Determines Pro- or Anti-Mitogenic Function
por: Hudson, Claire, et al.
Publicado: (2018)

Ending Restenosis: Inhibition of Vascular Smooth Muscle Cell Proliferation by cAMP
por: Smith, Sarah A., et al.
Publicado: (2019)

PKA and Epac synergistically inhibit smooth muscle cell proliferation
por: Hewer, Richard C., et al.
Publicado: (2011)

cAMP induces a rapid and reversible modification of the chemotactic receptor in Dictyostelium discoideum
Publicado: (1985)

Nuclear actin regulates cell proliferation and migration via inhibition of SRF and TEAD
por: McNeill, Madeleine C., et al.
Publicado: (2020)

S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo
por: Wu, Yih-Jer, et al.
Publicado: (2009)

cAMP Bursts Control T Cell Directionality by Actomyosin Cytoskeleton Remodeling
por: Simao, Morgane, et al.
Publicado: (2021)

Cyclic-AMP Increases Nuclear Actin Monomer Which Promotes Proteasomal Degradation of RelA/p65 Leading to Anti-Inflammatory Effects
por: Hawkins, Joseph W., et al.
Publicado: (2022)

Regulation of Epigenetic Modifiers, Including KDM6B, by Interferon-γ and Interleukin-4 in Human Macrophages
por: Yıldırım-Buharalıoğlu, Gökçe, et al.
Publicado: (2017)

MKL1-actin pathway restricts chromatin accessibility and prevents mature pluripotency activation
por: Hu, Xiao, et al.
Publicado: (2019)

cAMP-mediated inhibition of intracellular particle movement and actin reorganization in Dictyostelium
Publicado: (1989)

Release of cAMP Gating by the α6β4 Integrin Stimulates Lamellae Formation and the Chemotactic Migration of Invasive Carcinoma Cells
por: O'Connor, Kathleen L., et al.
Publicado: (1998)

Lamin A/C and emerin regulate MKL1/SRF activity by modulating actin dynamics
por: Ho, Chin Yee, et al.
Publicado: (2013)

Zoledronate upregulates MMP-9 and -13 in rat vascular smooth muscle cells by inducing oxidative stress
por: Arun, Mehmet Zuhuri, et al.
Publicado: (2016)

Synaptic localisation of SRF coactivators, MKL1 and MKL2, and their role in dendritic spine morphology
por: Kaneda, Marisa, et al.
Publicado: (2018)

cAMP and Ca(2+)-mediated secretion in parotid acinar cells is associated with reversible changes in the organization of the cytoskeleton
Publicado: (1992)

Actin cytoskeleton in angiogenesis
por: Yadunandanan Nair, Nidhi, et al.
Publicado: (2022)

Overexpression of scavenger receptor LOX-1 in endothelial cells promotes atherogenesis in the ApoE(−/−) mouse model
por: White, Stephen J., et al.
Publicado: (2011)

Effects of chemotactic factors and other agents on the amounts of actin and a 65,000-mol-wt protein associated with the cytoskeleton of rabbit and human neutrophils
Publicado: (1985)

Chemotactic peptide-induced changes in neutrophil actin conformation
Publicado: (1984)

Chemotactic peptide modulation of actin assembly and locomotion in neutrophils
Publicado: (1984)

Multiple Facets of cAMP Signalling and Physiological Impact: cAMP Compartmentalization in the Lung
por: Oldenburger, Anouk, et al.
Publicado: (2012)

Diverse patterns of cyclooxygenase-independent metalloproteinase gene regulation in human monocytes
por: Reel, Buket, et al.
Publicado: (2011)

cAMP crosses junctions
por: Bashyam, Hema
Publicado: (2007)

Mitochondrial cAMP signaling
por: Zhang, Fan, et al.
Publicado: (2016)

Dynamic reorganization of the actin cytoskeleton
por: Letort, Gaëlle, et al.
Publicado: (2015)

Regulation of the Actin Cytoskeleton in Podocytes
por: Blaine, Judith, et al.
Publicado: (2020)

Activation of the cAMP Pathway Induces RACK1-Dependent Binding of β-Actin to BDNF Promoter
por: Neasta, Jeremie, et al.
Publicado: (2016)

New Insights into the Function of the Matricellular CCN1: an Emerging Target in Proliferative Retinopathies
por: Chaqour, Brahim
Publicado: (2013)

An actin-nucleating activity in polymorphonuclear leukocytes is modulated by chemotactic peptides
Publicado: (1986)

Cyclic 3', 5'-AMP relay in dictyostelium discoideum. IV. Recovery of the cAMP signaling response after adaptation to cAMP
por: Dinauer, M, et al.
Publicado: (1980)

Cyclic 3', 5'-AMP relay dictyostelium discoideum. V. Adaptation of the cAMP signaling response during cAMP stimulation
por: Dinauer, M, et al.
Publicado: (1980)

Suppression of Virulence of Toxigenic Vibrio cholerae by Anethole through the Cyclic AMP (cAMP)-cAMP Receptor Protein Signaling System
por: Zahid, M. Shamim Hasan, et al.
Publicado: (2015)

Imaging cAMP nanodomains in the heart
por: Chao, Ying-Chi, et al.
Publicado: (2019)

Actin Cytoskeleton Regulates Hippo Signaling
por: Reddy, Pradeep, et al.
Publicado: (2013)

Regulation and integrated functions of the actin cytoskeleton
por: Charras, Guillaume, et al.
Publicado: (2016)

Regulation of Mitochondrial Function by the Actin Cytoskeleton
por: Illescas, María, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cq3b38rq3lpge0nbiilc569sg1