Redox regulation of cardiomyocyte cell cycling via an ERK1/2 and c-Myc-dependent activation of cyclin D2 transcription

Adult mammalian cardiomyocytes have a very limited capacity to proliferate, and consequently the loss of cells after cardiac stress promotes heart failure. Recent evidence suggests that administration of hydrogen peroxide (H(2)O(2)), can regulate redox-dependent signalling pathway(s) to promote card...

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Detalles Bibliográficos
Autores principales: Murray, Thomas V.A., Smyrnias, Ioannis, Schnelle, Moritz, Mistry, Rajesh K., Zhang, Min, Beretta, Matteo, Martin, Daniel, Anilkumar, Narayana, de Silva, Shana M., Shah, Ajay M., Brewer, Alison C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312357/
https://www.ncbi.nlm.nih.gov/pubmed/25450615
http://dx.doi.org/10.1016/j.yjmcc.2014.10.017

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