Proapoptotic Activity of a Monomeric Smac Mimetic on Human Fibroblast-Like Synoviocytes from Patients with Rheumatoid Arthritis

Inhibitors of apoptosis proteins (IAPs) block cell death in response to diverse stimuli. The mitochondrial protein, second mitochondria-derived activator of caspase (Smac), negatively regulates IAP inhibition of caspase activity. We investigated the proapoptotic activity of a synthetic Smac (Smac 06...

Descripción completa

Detalles Bibliográficos
Autores principales: Lattuada, D., Casnici, C., Crotta, K., Seneci, P.F., Corradini, C., Truzzi, M., Ingegnoli, F., Marelli, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312388/
https://www.ncbi.nlm.nih.gov/pubmed/25212046
http://dx.doi.org/10.1007/s10753-014-0012-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312388/
https://www.ncbi.nlm.nih.gov/pubmed/25212046
http://dx.doi.org/10.1007/s10753-014-0012-1

Ejemplares similares