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Proapoptotic Activity of a Monomeric Smac Mimetic on Human Fibroblast-Like Synoviocytes from Patients with Rheumatoid Arthritis

Inhibitors of apoptosis proteins (IAPs) block cell death in response to diverse stimuli. The mitochondrial protein, second mitochondria-derived activator of caspase (Smac), negatively regulates IAP inhibition of caspase activity. We investigated the proapoptotic activity of a synthetic Smac (Smac 06...

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Detalles Bibliográficos
Autores principales:	Lattuada, D., Casnici, C., Crotta, K., Seneci, P.F., Corradini, C., Truzzi, M., Ingegnoli, F., Marelli, O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312388/ https://www.ncbi.nlm.nih.gov/pubmed/25212046 http://dx.doi.org/10.1007/s10753-014-0012-1

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