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Positive regulation of Rho GTPase activity by RhoGDIs as a result of their direct interaction with GAPs
BACKGROUND: Rho GTPases function as molecular switches in many different signaling pathways and control a wide range of cellular processes. Rho GDP-dissociation inhibitors (RhoGDIs) regulate Rho GTPase signaling and can function as both negative and positive regulators. The role of RhoGDIs as negati...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312443/ https://www.ncbi.nlm.nih.gov/pubmed/25628036 http://dx.doi.org/10.1186/s12918-015-0143-5 |