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Reduced Krüppel-like Factor 2 expression may aggravate the endothelial injury of diabetic nephropathy

Kruppel-like Factor 2 (KLF2), a shear-stress inducible transcription factor, has endoprotective effects. In streptozotocin-induced diabetic rats, we found that glomerular Klf2 expression was reduced in comparison to non-diabetic rats. However, normalization of hyperglycemia by insulin treatment incr...

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Detalles Bibliográficos
Autores principales:	Zhong, Fang, Chen, Habing, Wei, Chengguo, Zhang, Weijia, Li, Zhengzhe, Jain, Mukesh K, Chuang, Peter Y., Chen, Hongyu, Wang, Yongjun, Mallipattu, Sandeep K., He, John Cijiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312548/ https://www.ncbi.nlm.nih.gov/pubmed/25185079 http://dx.doi.org/10.1038/ki.2014.286

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