Dual B Cell Immunotherapy Is Superior to Individual Anti-CD20 Depletion or BAFF Blockade in Murine Models of Spontaneous or Accelerated Lupus

OBJECTIVE: To determine whether a combination of B cell depletion and BAFF blockade is more effective than monotherapy in treating models of spontaneous or accelerated systemic lupus erythematosus (SLE) in (NZB × NZW)F1 mice. METHODS: Clinical parameters such as disease progression–free survival, pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, WeiYu, Seshasayee, Dhaya, Lee, Wyne P, Caplazi, Patrick, McVay, Sami, Suto, Eric, Nguyen, Allen, Lin, Zhonghua, Sun, Yonglian, DeForge, Laura, Balazs, Mercedesz, Martin, Flavius, Zarrin, Ali A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Systemic Lupus Erythematosus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312898/
https://www.ncbi.nlm.nih.gov/pubmed/25303150
http://dx.doi.org/10.1002/art.38907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312898/
https://www.ncbi.nlm.nih.gov/pubmed/25303150
http://dx.doi.org/10.1002/art.38907

Ejemplares similares