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Perforin-like protein PPLP2 permeabilizes the red blood cell membrane during egress of Plasmodium falciparum gametocytes
Egress of malaria parasites from the host cell requires the concerted rupture of its enveloping membranes. Hence, we investigated the role of the plasmodial perforin-like protein PPLP2 in the egress of Plasmodium falciparum from erythrocytes. PPLP2 is expressed in blood stage schizonts and mature ga...
Autores principales: | Wirth, Christine C, Glushakova, Svetlana, Scheuermayer, Matthias, Repnik, Urska, Garg, Swati, Schaack, Dominik, Kachman, Marika M, Weißbach, Tim, Zimmerberg, Joshua, Dandekar, Thomas, Griffiths, Gareth, Chitnis, Chetan E, Singh, Shailja, Fischer, Rainer, Pradel, Gabriele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312913/ https://www.ncbi.nlm.nih.gov/pubmed/24602217 http://dx.doi.org/10.1111/cmi.12288 |
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