Cargando…

p21/Cyclin E pathway modulates anticlastogenic function of Bmi-1 in cancer cells

Apart from regulating stem cell self-renewal, embryonic development and proliferation, Bmi-1 has been recently reported to be critical in the maintenance of genome integrity. In searching for novel mechanisms underlying the anticlastogenic function of Bmi-1, we observed, for the first time, that Bmi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deng, Wen, Zhou, Yuan, Tiwari, Agnes FY, Su, Hang, Yang, Jie, Zhu, Dandan, Lau, Victoria Ming Yi, Hau, Pok Man, Yip, Yim Ling, Cheung, Annie LM, Guan, Xin-Yuan, Tsao, Sai Wah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2015
Materias:	Cancer Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312942/ https://www.ncbi.nlm.nih.gov/pubmed/25131797 http://dx.doi.org/10.1002/ijc.29114

Ejemplares similares

Extremely stringent activation of p16(INK4a) prevents immortalization of uterine cervical epithelial cells without human papillomavirus oncogene expression
por: Hang, Su, et al.
Publicado: (2016)

Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Impairs G2 Checkpoint in Human Nasopharyngeal Epithelial Cells through Defective Chk1 Activation
por: Deng, Wen, et al.
Publicado: (2012)

Antioxidant and Anticlastogenic Capacity of Prickly Pear Juice
por: Madrigal-Santillán, Eduardo, et al.
Publicado: (2013)

Id1 Interacts and Stabilizes the Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) in Nasopharyngeal Epithelial Cells
por: Hau, Pok Man, et al.
Publicado: (2011)

Epstein–Barr Virus Hijacks DNA Damage Response Transducers to Orchestrate Its Life Cycle
por: Hau, Pok Man, et al.
Publicado: (2017)

Anticlastogenic activity of flavonoid reach extract of Cassia auriculata Linn. on experimental animal
por: Deshpande, Supriya S., et al.
Publicado: (2013)

In vivo anticlastogenic effect of silymarin from milk thistle Silybum marianum L.
por: Anwar, Sirajudheen, et al.
Publicado: (2018)

Anticlastogenic, radiation antagonistic, and anti-inflammatory activities of Persea americana in albino Wistar rat model
por: Kumar, Amith, et al.
Publicado: (2017)

Efficient Immortalization of Primary Nasopharyngeal Epithelial Cells for EBV Infection Study
por: Yip, Yim Ling, et al.
Publicado: (2013)

Enhanced IL-6/IL-6R Signaling Promotes Growth and Malignant Properties in EBV-Infected Premalignant and Cancerous Nasopharyngeal Epithelial Cells
por: Zhang, Guitao, et al.
Publicado: (2013)

Antimutagenic and anticlastogenic effects of Turkish Black Tea on TA98 and TA100 strains of Salmonella typhimurium (in vitro) and mice (in vivo)
por: Charehsaz, Mohammad, et al.
Publicado: (2017)

Targeting VEGFR1- and VEGFR2-expressing non-tumor cells is essential for esophageal cancer therapy
por: Xu, Wen Wen, et al.
Publicado: (2014)

Pericentromeric Regions Are Refractory To Prompt Repair after Replication Stress-Induced Breakage in HPV16 E6E7-Expressing Epithelial Cells
por: Deng, Wen, et al.
Publicado: (2012)

Cyclin Kinase-independent role of p21(CDKN1A) in the promotion of nascent DNA elongation in unstressed cells
por: Mansilla, Sabrina F, et al.
Publicado: (2016)

DNA methylome analysis identifies BMI‐related epigenetic changes associated with non‐small cell lung cancer susceptibility
por: Li, Guyanan, et al.
Publicado: (2021)

Exosomes derived from γδ-T cells synergize with radiotherapy and preserve antitumor activities against nasopharyngeal carcinoma in immunosuppressive microenvironment
por: Wang, Xiwei, et al.
Publicado: (2022)

Isoliquiritigenin inhibits the proliferation, migration and metastasis of Hep3B cells via suppressing cyclin D1 and PI3K/AKT pathway
por: Huang, Yun, et al.
Publicado: (2020)

Berberine Suppresses Cyclin D1 Expression through Proteasomal Degradation in Human Hepatoma Cells
por: Wang, Ning, et al.
Publicado: (2016)

Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway
por: Li, Bin, et al.
Publicado: (2014)

Downregulation of AGR2, p21, and cyclin D and alterations in p53 function were associated with tumor progression and chemotherapy resistance in epithelial ovarian carcinoma
por: Alves, Mariana Rezende, et al.
Publicado: (2018)

Epigenetically altered miR-193b targets cyclin D1 in prostate cancer
por: Kaukoniemi, Kirsi M, et al.
Publicado: (2015)

PGC‐1α inhibits polyamine metabolism in Cyclin E1‐driven ovarian cancer
por: Guo, Ting, et al.
Publicado: (2019)

Racial/ethnic disparities in weight or BMI change in adulthood and pancreatic cancer incidence: The multiethnic cohort
por: Farias, Albert J., et al.
Publicado: (2021)

Epstein-Barr virus infection and persistence in nasopharyngeal epithelial cells
por: Tsang, Chi Man, et al.
Publicado: (2014)

Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts
por: Tsang, Chi Man, et al.
Publicado: (2013)

miR-219-5p targets TBXT and inhibits breast cancer cell EMT and cell migration and invasion
por: Ye, Qin, et al.
Publicado: (2021)

Identification of novel cyclin gene fusion transcripts in endometrioid ovarian carcinomas
por: Agostini, Antonio, et al.
Publicado: (2018)

Comprehensive Landscape of Cyclin Pathway Gene Alterations and Co-occurrence with FGF/FGFR Aberrations Across Urinary Tract Tumors
por: Jardim, Denis L F, et al.
Publicado: (2022)

Association between blood pressure and BMI with bladder cancer risk and mortality in 340,000 men in three Swedish cohorts
por: Teleka, Stanley, et al.
Publicado: (2021)

Loss of cyclin‐dependent kinase‐like 2 predicts poor prognosis in gastric cancer, and its overexpression suppresses cells growth and invasion
por: Fang, Chia‐Lang, et al.
Publicado: (2018)

Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2
por: Enrico, Taylor P, et al.
Publicado: (2021)

BMI trajectories and risk of overall and grade‐specific prostate cancer: An observational cohort study among men seen for prostatic conditions
por: Wang, Kai, et al.
Publicado: (2018)

Clinical Management of Potential Toxicities and Drug Interactions Related to Cyclin‐Dependent Kinase 4/6 Inhibitors in Breast Cancer: Practical Considerations and Recommendations
por: Spring, Laura M., et al.
Publicado: (2017)

CCN1 stimulated the osteoblasts via PTEN/AKT/GSK3β/cyclinD1 signal pathway in Myeloma Bone Disease
por: Yan, Siyang, et al.
Publicado: (2019)

Significance of PI3K/AKT signaling pathway in metastasis of esophageal squamous cell carcinoma and its potential as a target for anti-metastasis therapy
por: Li, Bin, et al.
Publicado: (2017)

Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression
por: Xu, Wen Wen, et al.
Publicado: (2017)

The poor outcome of second primary oral squamous cell carcinoma is attributed to Bmi1 upregulation
por: Hu, Qinchao, et al.
Publicado: (2018)

Association between proton pump inhibitors after percutaneous coronary intervention and risk of gastric cancer
por: Ng, Andrew Kei-Yan, et al.
Publicado: (2021)

Baseline BMI and BMI variation during first line pembrolizumab in NSCLC patients with a PD-L1 expression ≥ 50%: a multicenter study with external validation
por: Cortellini, Alessio, et al.
Publicado: (2020)

p85β alters response to EGFR inhibitor in ovarian cancer through p38 MAPK-mediated regulation of DNA repair
por: Mak, Victor CY, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_abu4u39si47j8ctoof5458hipj