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Computational Study of Correlated Domain Motions in the AcrB Efflux Transporter

As active part of the major efflux system in E. coli bacteria, AcrB is responsible for the uptake and pumping of toxic substrates from the periplasm toward the extracellular space. In combination with the channel protein TolC and membrane fusion protein AcrA, this efflux pump is able to help the bac...

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Detalles Bibliográficos
Autores principales: Schulz, Robert, Vargiu, Attilio V., Ruggerone, Paolo, Kleinekathöfer, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313061/
https://www.ncbi.nlm.nih.gov/pubmed/25685792
http://dx.doi.org/10.1155/2015/487298