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Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling

Human cancer cell lines are used as important model systems to study molecular mechanisms associated with tumor growth, hereunder how genomic and biological heterogeneity found in primary tumors affect cellular phenotypes. We reconstructed Genome scale metabolic models (GEMs) for eleven cell lines b...

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Detalles Bibliográficos
Autores principales:	Ghaffari, Pouyan, Mardinoglu, Adil, Asplund, Anna, Shoaie, Saeed, Kampf, Caroline, Uhlen, Mathias, Nielsen, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313100/ https://www.ncbi.nlm.nih.gov/pubmed/25640694 http://dx.doi.org/10.1038/srep08183

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