Cargando…
Enhancer Evolution across 20 Mammalian Species
The mammalian radiation has corresponded with rapid changes in noncoding regions of the genome, but we lack a comprehensive understanding of regulatory evolution in mammals. Here, we track the evolution of promoters and enhancers active in liver across 20 mammalian species from six diverse orders by...
Autores principales: | Villar, Diego, Berthelot, Camille, Aldridge, Sarah, Rayner, Tim F., Lukk, Margus, Pignatelli, Miguel, Park, Thomas J., Deaville, Robert, Erichsen, Jonathan T., Jasinska, Anna J., Turner, James M.A., Bertelsen, Mads F., Murchison, Elizabeth P., Flicek, Paul, Odom, Duncan T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313353/ https://www.ncbi.nlm.nih.gov/pubmed/25635462 http://dx.doi.org/10.1016/j.cell.2015.01.006 |
Ejemplares similares
-
Complexity and conservation of regulatory landscapes underlie evolutionary resilience of mammalian gene expression
por: Berthelot, Camille, et al.
Publicado: (2017) -
AHT-ChIP-seq: a completely automated robotic protocol for high-throughput chromatin immunoprecipitation
por: Aldridge, Sarah, et al.
Publicado: (2013) -
Crisflash: open-source software to generate CRISPR guide RNAs against genomes annotated with individual variation
por: Jacquin, Adrien L S, et al.
Publicado: (2019) -
Mutational landscape of a chemically-induced mouse model of liver cancer
por: Connor, Frances, et al.
Publicado: (2018) -
Global Gene Expression Profiling Reveals SPINK1 as a Potential Hepatocellular Carcinoma Marker
por: Marshall, Aileen, et al.
Publicado: (2013)