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Pneumomediastinum as a complication of SABR for lung metastases
BACKGROUND: Stereotactic ablative body radiation (SABR) is a novel and sophisticated radiation modality that involves the irradiation of extracranial tumors through precise and very high doses in patients with oligometastatic lung disease and primary lung tumors. CASE PRESENTATION: A 52-year-old fem...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313462/ https://www.ncbi.nlm.nih.gov/pubmed/25612575 http://dx.doi.org/10.1186/s13014-015-0330-y |
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author | Rodríguez-Ruiz, María Esperanza Arévalo, Estefanía Gil-Bazo, Ignacio García, Alicia Olarte Valtueña, German Moreno-Jiménez, Marta Arbea-Moreno, Leire Aristu, Javier |
author_facet | Rodríguez-Ruiz, María Esperanza Arévalo, Estefanía Gil-Bazo, Ignacio García, Alicia Olarte Valtueña, German Moreno-Jiménez, Marta Arbea-Moreno, Leire Aristu, Javier |
author_sort | Rodríguez-Ruiz, María Esperanza |
collection | PubMed |
description | BACKGROUND: Stereotactic ablative body radiation (SABR) is a novel and sophisticated radiation modality that involves the irradiation of extracranial tumors through precise and very high doses in patients with oligometastatic lung disease and primary lung tumors. CASE PRESENTATION: A 52-year-old female with subclinical idiopathic interstitial lung disease (ILD) and oligometastatic lung disease from squamous urethral cancer who was treated with SABR for a metastatic lesion located in the right lower pulmonary lobe. The patient received a hypo-fractionated course of SABR. A 3D-conformal multifield technique was used with six coplanar and one non-coplanar statics beams. A 48 Gy total dose in three fractions over six days was prescribed to the 95% of the PTV. The presence of idiopathic ILD and other identifiable underlying lung conditions were not taken into account as a constraint to prescribe a different than standard total dose or fractionation schedule. Six months after the SABR treatment, a CT-scan showed the presence of a pneumomediastinum with air outside the bronchial tree and within the subcutaneous tissue without co-existing pneumothorax. To our knowledge, this is the first case of pneumomediastinum appearing 6 months after SABR treatment for a lung metastasis located in the perihiliar/central tumors region as defined by the RTOG protocols as the proximal bronchial tree. CONCLUSION: Radiation oncologist should be aware of the potential risk of severe lung toxicity caused by SABR in patients with ILD, especially when chemotherapy-induced pulmonary toxicity is administered in a short time interval. |
format | Online Article Text |
id | pubmed-4313462 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-43134622015-02-03 Pneumomediastinum as a complication of SABR for lung metastases Rodríguez-Ruiz, María Esperanza Arévalo, Estefanía Gil-Bazo, Ignacio García, Alicia Olarte Valtueña, German Moreno-Jiménez, Marta Arbea-Moreno, Leire Aristu, Javier Radiat Oncol Case Report BACKGROUND: Stereotactic ablative body radiation (SABR) is a novel and sophisticated radiation modality that involves the irradiation of extracranial tumors through precise and very high doses in patients with oligometastatic lung disease and primary lung tumors. CASE PRESENTATION: A 52-year-old female with subclinical idiopathic interstitial lung disease (ILD) and oligometastatic lung disease from squamous urethral cancer who was treated with SABR for a metastatic lesion located in the right lower pulmonary lobe. The patient received a hypo-fractionated course of SABR. A 3D-conformal multifield technique was used with six coplanar and one non-coplanar statics beams. A 48 Gy total dose in three fractions over six days was prescribed to the 95% of the PTV. The presence of idiopathic ILD and other identifiable underlying lung conditions were not taken into account as a constraint to prescribe a different than standard total dose or fractionation schedule. Six months after the SABR treatment, a CT-scan showed the presence of a pneumomediastinum with air outside the bronchial tree and within the subcutaneous tissue without co-existing pneumothorax. To our knowledge, this is the first case of pneumomediastinum appearing 6 months after SABR treatment for a lung metastasis located in the perihiliar/central tumors region as defined by the RTOG protocols as the proximal bronchial tree. CONCLUSION: Radiation oncologist should be aware of the potential risk of severe lung toxicity caused by SABR in patients with ILD, especially when chemotherapy-induced pulmonary toxicity is administered in a short time interval. BioMed Central 2015-01-23 /pmc/articles/PMC4313462/ /pubmed/25612575 http://dx.doi.org/10.1186/s13014-015-0330-y Text en © Rodriguez-Ruiz et al. ; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Rodríguez-Ruiz, María Esperanza Arévalo, Estefanía Gil-Bazo, Ignacio García, Alicia Olarte Valtueña, German Moreno-Jiménez, Marta Arbea-Moreno, Leire Aristu, Javier Pneumomediastinum as a complication of SABR for lung metastases |
title | Pneumomediastinum as a complication of SABR for lung metastases |
title_full | Pneumomediastinum as a complication of SABR for lung metastases |
title_fullStr | Pneumomediastinum as a complication of SABR for lung metastases |
title_full_unstemmed | Pneumomediastinum as a complication of SABR for lung metastases |
title_short | Pneumomediastinum as a complication of SABR for lung metastases |
title_sort | pneumomediastinum as a complication of sabr for lung metastases |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313462/ https://www.ncbi.nlm.nih.gov/pubmed/25612575 http://dx.doi.org/10.1186/s13014-015-0330-y |
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