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Development of a Mild and Versatile Directed Cycloaddition Approach to Pyridines

The aza-Diels–Alder cycloaddition of 1,2,4-triazines with alkynes offers a rapid and convenient method for the synthesis of highly substituted pyridines, but often requires harsh conditions and long reaction times. The present study offers a solution to these limitations by use of a temporary tether...

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Detalles Bibliográficos
Autores principales: Bachollet, Sylvestre P J T, Vivat, Jérôme F, Cocker, Dean C, Adams, Harry, Harrity, Joseph P A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313684/
https://www.ncbi.nlm.nih.gov/pubmed/25145488
http://dx.doi.org/10.1002/chem.201403916