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Development of a Mild and Versatile Directed Cycloaddition Approach to Pyridines
The aza-Diels–Alder cycloaddition of 1,2,4-triazines with alkynes offers a rapid and convenient method for the synthesis of highly substituted pyridines, but often requires harsh conditions and long reaction times. The present study offers a solution to these limitations by use of a temporary tether...
Autores principales: | Bachollet, Sylvestre P J T, Vivat, Jérôme F, Cocker, Dean C, Adams, Harry, Harrity, Joseph P A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313684/ https://www.ncbi.nlm.nih.gov/pubmed/25145488 http://dx.doi.org/10.1002/chem.201403916 |
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