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Evaluation of the Potential Impact of Ebola Virus Genomic Drift on the Efficacy of Sequence-Based Candidate Therapeutics

Until recently, Ebola virus (EBOV) was a rarely encountered human pathogen that caused disease among small populations with extraordinarily high lethality. At the end of 2013, EBOV initiated an unprecedented disease outbreak in West Africa that is still ongoing and has already caused thousands of de...

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Detalles Bibliográficos
Autores principales: Kugelman, Jeffrey R., Sanchez-Lockhart, Mariano, Andersen, Kristian G., Gire, Stephen, Park, Daniel J., Sealfon, Rachel, Lin, Aaron E., Wohl, Shirlee, Sabeti, Pardis C., Kuhn, Jens H., Palacios, Gustavo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313914/
https://www.ncbi.nlm.nih.gov/pubmed/25604787
http://dx.doi.org/10.1128/mBio.02227-14

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