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Inhibitor of DNA Binding 4 (ID4) Is Highly Expressed in Human Melanoma Tissues and May Function to Restrict Normal Differentiation of Melanoma Cells

Melanoma tissues and cell lines are heterogeneous, and include cells with invasive, proliferative, stem cell-like, and differentiated properties. Such heterogeneity likely contributes to the aggressiveness of the disease and resistance to therapy. One model suggests that heterogeneity arises from ra...

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Detalles Bibliográficos
Autores principales: Peretz, Yuval, Wu, Hong, Patel, Shayan, Bellacosa, Alfonso, Katz, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314081/
https://www.ncbi.nlm.nih.gov/pubmed/25642713
http://dx.doi.org/10.1371/journal.pone.0116839