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Inhibitor of DNA Binding 4 (ID4) Is Highly Expressed in Human Melanoma Tissues and May Function to Restrict Normal Differentiation of Melanoma Cells
Melanoma tissues and cell lines are heterogeneous, and include cells with invasive, proliferative, stem cell-like, and differentiated properties. Such heterogeneity likely contributes to the aggressiveness of the disease and resistance to therapy. One model suggests that heterogeneity arises from ra...
Autores principales: | Peretz, Yuval, Wu, Hong, Patel, Shayan, Bellacosa, Alfonso, Katz, Richard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314081/ https://www.ncbi.nlm.nih.gov/pubmed/25642713 http://dx.doi.org/10.1371/journal.pone.0116839 |
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