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Stimulation of Oligonucleotide-Directed Gene Correction by Redβ Expression and MSH2 Depletion in Human HT1080 Cells

The correction of disease-causing mutations by single-strand oligonucleotide-templated DNA repair (ssOR) is an attractive approach to gene therapy, but major improvements in ssOR efficiency and consistency are needed. The mechanism of ssOR is poorly understood but may involve annealing of oligonucle...

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Detalles Bibliográficos
Autores principales:	Xu, Ke, Stewart, A. Francis, Porter, Andrew C.G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314130/ https://www.ncbi.nlm.nih.gov/pubmed/25431426 http://dx.doi.org/10.14348/molcells.2015.2163

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