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TLR4 Mediates Pneumolysin-Induced ATF3 Expression through the JNK/p38 Pathway in Streptococcus pneumoniae-Infected RAW 264.7 Cells

Activating transcription factor-3 (ATF3) acts as a negative regulator of cytokine production during Gram-negative bacterial infection. A recent study reported that ATF3 provides protection from Streptococcus pneumoniae infection by activating cytokines. However, the mechanism by which S. pneumoniae...

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Detalles Bibliográficos
Autores principales: Nguyen, Cuong Thach, Kim, Eun-Hye, Luong, Truc Thanh, Pyo, Suhkneung, Rhee, Dong-Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314132/
https://www.ncbi.nlm.nih.gov/pubmed/25518930
http://dx.doi.org/10.14348/molcells.2015.2231