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A Targeted Health Risk Assessment Following the Deepwater Horizon Oil Spill: Polycyclic Aromatic Hydrocarbon Exposure in Vietnamese-American Shrimp Consumers
Background: The Deepwater Horizon oil spill of 2010 prompted concern about health risks among seafood consumers exposed to polycyclic aromatic hydrocarbons (PAHs) via consumption of contaminated seafood. Objective: The objective of this study was to conduct population-specific probabilistic health r...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
NLM-Export
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314254/ https://www.ncbi.nlm.nih.gov/pubmed/25333566 http://dx.doi.org/10.1289/ehp.1408684 |
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author | Wilson, Mark J. Frickel, Scott Nguyen, Daniel Bui, Tap Echsner, Stephen Simon, Bridget R. Howard, Jessi L. Miller, Kent Wickliffe, Jeffrey K. |
author_facet | Wilson, Mark J. Frickel, Scott Nguyen, Daniel Bui, Tap Echsner, Stephen Simon, Bridget R. Howard, Jessi L. Miller, Kent Wickliffe, Jeffrey K. |
author_sort | Wilson, Mark J. |
collection | PubMed |
description | Background: The Deepwater Horizon oil spill of 2010 prompted concern about health risks among seafood consumers exposed to polycyclic aromatic hydrocarbons (PAHs) via consumption of contaminated seafood. Objective: The objective of this study was to conduct population-specific probabilistic health risk assessments based on consumption of locally harvested white shrimp (Litopenaeus setiferus) among Vietnamese Americans in southeast Louisiana. Methods: We conducted a survey of Vietnamese Americans in southeast Louisiana to evaluate shrimp consumption, preparation methods, and body weight among shrimp consumers in the disaster-impacted region. We also collected and chemically analyzed locally harvested white shrimp for 81 individual PAHs. We combined the PAH levels (with accepted reference doses) found in the shrimp with the survey data to conduct Monte Carlo simulations for probabilistic noncancer health risk assessments. We also conducted probabilistic cancer risk assessments using relative potency factors (RPFs) to estimate cancer risks from the intake of PAHs from white shrimp. Results: Monte Carlo simulations were used to generate hazard quotient distributions for noncancer health risks, reported as mean ± SD, for naphthalene (1.8 × 10(–4) ± 3.3 × 10(–4)), fluorene (2.4 × 10(–5) ± 3.3 × 10(–5)), anthracene (3.9 × 10(–6) ± 5.4 × 10(–6)), pyrene (3.2 × 10(–5) ± 4.3 × 10(–5)), and fluoranthene (1.8 × 10(–4) ± 3.3 × 10(–4)). A cancer risk distribution, based on RPF-adjusted PAH intake, was also generated (2.4 × 10(–7) ± 3.9 × 10(–7)). Conclusions: The risk assessment results show no acute health risks or excess cancer risk associated with consumption of shrimp containing the levels of PAHs detected in our study, even among frequent shrimp consumers. Citation: Wilson MJ, Frickel S, Nguyen D, Bui T, Echsner S, Simon BR, Howard JL, Miller K, Wickliffe JK. 2015. A targeted health risk assessment following the Deepwater Horizon Oil Spill: polycyclic aromatic hydrocarbon exposure in Vietnamese-American shrimp consumers. Environ Health Perspect 123:152–159; http://dx.doi.org/10.1289/ehp.1408684 |
format | Online Article Text |
id | pubmed-4314254 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | NLM-Export |
record_format | MEDLINE/PubMed |
spelling | pubmed-43142542015-02-06 A Targeted Health Risk Assessment Following the Deepwater Horizon Oil Spill: Polycyclic Aromatic Hydrocarbon Exposure in Vietnamese-American Shrimp Consumers Wilson, Mark J. Frickel, Scott Nguyen, Daniel Bui, Tap Echsner, Stephen Simon, Bridget R. Howard, Jessi L. Miller, Kent Wickliffe, Jeffrey K. Environ Health Perspect Research Background: The Deepwater Horizon oil spill of 2010 prompted concern about health risks among seafood consumers exposed to polycyclic aromatic hydrocarbons (PAHs) via consumption of contaminated seafood. Objective: The objective of this study was to conduct population-specific probabilistic health risk assessments based on consumption of locally harvested white shrimp (Litopenaeus setiferus) among Vietnamese Americans in southeast Louisiana. Methods: We conducted a survey of Vietnamese Americans in southeast Louisiana to evaluate shrimp consumption, preparation methods, and body weight among shrimp consumers in the disaster-impacted region. We also collected and chemically analyzed locally harvested white shrimp for 81 individual PAHs. We combined the PAH levels (with accepted reference doses) found in the shrimp with the survey data to conduct Monte Carlo simulations for probabilistic noncancer health risk assessments. We also conducted probabilistic cancer risk assessments using relative potency factors (RPFs) to estimate cancer risks from the intake of PAHs from white shrimp. Results: Monte Carlo simulations were used to generate hazard quotient distributions for noncancer health risks, reported as mean ± SD, for naphthalene (1.8 × 10(–4) ± 3.3 × 10(–4)), fluorene (2.4 × 10(–5) ± 3.3 × 10(–5)), anthracene (3.9 × 10(–6) ± 5.4 × 10(–6)), pyrene (3.2 × 10(–5) ± 4.3 × 10(–5)), and fluoranthene (1.8 × 10(–4) ± 3.3 × 10(–4)). A cancer risk distribution, based on RPF-adjusted PAH intake, was also generated (2.4 × 10(–7) ± 3.9 × 10(–7)). Conclusions: The risk assessment results show no acute health risks or excess cancer risk associated with consumption of shrimp containing the levels of PAHs detected in our study, even among frequent shrimp consumers. Citation: Wilson MJ, Frickel S, Nguyen D, Bui T, Echsner S, Simon BR, Howard JL, Miller K, Wickliffe JK. 2015. A targeted health risk assessment following the Deepwater Horizon Oil Spill: polycyclic aromatic hydrocarbon exposure in Vietnamese-American shrimp consumers. Environ Health Perspect 123:152–159; http://dx.doi.org/10.1289/ehp.1408684 NLM-Export 2014-10-21 2015-02 /pmc/articles/PMC4314254/ /pubmed/25333566 http://dx.doi.org/10.1289/ehp.1408684 Text en http://creativecommons.org/publicdomain/mark/1.0/ Publication of EHP lies in the public domain and is therefore without copyright. All text from EHP may be reprinted freely. Use of materials published in EHP should be acknowledged (for example, “Reproduced with permission from Environmental Health Perspectives”); pertinent reference information should be provided for the article from which the material was reproduced. Articles from EHP, especially the News section, may contain photographs or illustrations copyrighted by other commercial organizations or individuals that may not be used without obtaining prior approval from the holder of the copyright. |
spellingShingle | Research Wilson, Mark J. Frickel, Scott Nguyen, Daniel Bui, Tap Echsner, Stephen Simon, Bridget R. Howard, Jessi L. Miller, Kent Wickliffe, Jeffrey K. A Targeted Health Risk Assessment Following the Deepwater Horizon Oil Spill: Polycyclic Aromatic Hydrocarbon Exposure in Vietnamese-American Shrimp Consumers |
title | A Targeted Health Risk Assessment Following the Deepwater Horizon Oil Spill: Polycyclic Aromatic Hydrocarbon Exposure in Vietnamese-American Shrimp Consumers |
title_full | A Targeted Health Risk Assessment Following the Deepwater Horizon Oil Spill: Polycyclic Aromatic Hydrocarbon Exposure in Vietnamese-American Shrimp Consumers |
title_fullStr | A Targeted Health Risk Assessment Following the Deepwater Horizon Oil Spill: Polycyclic Aromatic Hydrocarbon Exposure in Vietnamese-American Shrimp Consumers |
title_full_unstemmed | A Targeted Health Risk Assessment Following the Deepwater Horizon Oil Spill: Polycyclic Aromatic Hydrocarbon Exposure in Vietnamese-American Shrimp Consumers |
title_short | A Targeted Health Risk Assessment Following the Deepwater Horizon Oil Spill: Polycyclic Aromatic Hydrocarbon Exposure in Vietnamese-American Shrimp Consumers |
title_sort | targeted health risk assessment following the deepwater horizon oil spill: polycyclic aromatic hydrocarbon exposure in vietnamese-american shrimp consumers |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314254/ https://www.ncbi.nlm.nih.gov/pubmed/25333566 http://dx.doi.org/10.1289/ehp.1408684 |
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