Chronic alcohol exposure exacerbates inflammation and triggers pancreatic acinar-to-ductal metaplasia through PI3K/Akt/IKK

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Pancreatic acinar-to-ductal metaplasia (ADM) has been identified as an initiating event that can progress to pancreatic intraepithelial neoplasia (PanIN) or pancreatic ductal adenocarcinoma (PDAC). Acini transdifferentiation can be induced by persistent inflammation. Notably, compelling evidence has...

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Detalles Bibliográficos
Autores principales: HUANG, XIN, LI, XUQI, MA, QINGYONG, XU, QINHONG, DUAN, WANXING, LEI, JIANJUN, ZHANG, LUN, WU, ZHENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314411/
https://www.ncbi.nlm.nih.gov/pubmed/25573338
http://dx.doi.org/10.3892/ijmm.2014.2055
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