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Differential effects of angiopoietin-like 4 in brain and muscle on regulation of lipoprotein lipase activity

OBJECTIVE: Lipoprotein lipase (LPL) is a key regulator of circulating triglyceride rich lipoprotein hydrolysis. In brain LPL regulates appetite and energy expenditure. Angiopoietin-like 4 (Angptl4) is a secreted protein that inhibits LPL activity and, thereby, triglyceride metabolism, but the impact...

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Detalles Bibliográficos
Autores principales: Vienberg, Sara Gry, Kleinridders, André, Suzuki, Ryo, Kahn, C. Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314546/
https://www.ncbi.nlm.nih.gov/pubmed/25685701
http://dx.doi.org/10.1016/j.molmet.2014.11.003