Mechanisms of Gefitinib-mediated reversal of tamoxifen resistance in MCF-7 breast cancer cells by inducing ERα re-expression

Estrogen receptor (ER)-positive breast cancer patients may turn ER-negative and develop acquired drug resistance, which compromises the efficacy of endocrine therapy. By investigating the phenomenon that gefitinib can re-sensitise tamoxifen (TAM)-resistant MCF-7 breast cancer cells (MCF-7/TAM) to TA...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xia, Zhang, Bin, Liu, Jie, Liu, Jiwei, Li, Changzheng, Dong, Wei, Fang, Shu, Li, Minmin, Song, Bao, Tang, Bo, Wang, Zhehai, Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314651/
https://www.ncbi.nlm.nih.gov/pubmed/25644501
http://dx.doi.org/10.1038/srep07835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314651/
https://www.ncbi.nlm.nih.gov/pubmed/25644501
http://dx.doi.org/10.1038/srep07835

Ejemplares similares