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The matricellular protein CCN3 regulates NOTCH1 signalling in chronic myeloid leukaemia

Deregulated NOTCH1 has been reported in lymphoid leukaemia, although its role in chronic myeloid leukaemia (CML) is not well established. We previously reported BCR-ABL down-regulation of a novel haematopoietic regulator, CCN3, in CML; CCN3 is a non-canonical NOTCH1 ligand. This study characterizes...

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Detalles Bibliográficos
Autores principales: Suresh, Sukanya, McCallum, Lynn, Crawford, Lisa J, Lu, Wan Hua, Sharpe, Daniel J, Irvine, Alexandra E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314772/
https://www.ncbi.nlm.nih.gov/pubmed/24308033
http://dx.doi.org/10.1002/path.4246

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