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Morphological and physiological retinal degeneration induced by intravenous delivery of vitamin A dimers in rabbits
The eye uses vitamin A as a cofactor to sense light and, during this process, some vitamin A molecules dimerize, forming vitamin A dimers. A striking chemical signature of retinas undergoing degeneration in major eye diseases such as age-related macular degeneration (AMD) and Stargardt disease is th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Limited
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314778/ https://www.ncbi.nlm.nih.gov/pubmed/25504631 http://dx.doi.org/10.1242/dmm.017194 |