Impact of retinoic acid exposure on midfacial shape variation and manifestation of holoprosencephaly in Twsg1 mutant mice

Holoprosencephaly (HPE) is a developmental anomaly characterized by inadequate or absent midline division of the embryonic forebrain and midline facial defects. It is believed that interactions between genes and the environment play a role in the widely variable penetrance and expressivity of HPE, a...

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Detalles Bibliográficos
Autores principales: Billington, Charles J., Schmidt, Brian, Marcucio, Ralph S., Hallgrimsson, Benedikt, Gopalakrishnan, Rajaram, Petryk, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314779/
https://www.ncbi.nlm.nih.gov/pubmed/25468951
http://dx.doi.org/10.1242/dmm.018275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314779/
https://www.ncbi.nlm.nih.gov/pubmed/25468951
http://dx.doi.org/10.1242/dmm.018275

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