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Autopsy study of febrile deaths during monsoon at a tertiary care institute in India: Is malaria still a challenge?

BACKGROUND: To utilise an autopsy-based approach to study the febrile deaths and deaths due to malaria during monsoon period of three years at a tertiary care teaching hospital in Mumbai, India. MATERIALS AND METHODS: All autopsies done at the hospital during monsoon period from 2005 to 2007 when fe...

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Autores principales: Gupta, Anurag, Dhume, Varsha, Puranik, Gururaj Venkatesh, Kavishwar, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314863/
https://www.ncbi.nlm.nih.gov/pubmed/25657486
http://dx.doi.org/10.4103/0300-1652.149163
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author Gupta, Anurag
Dhume, Varsha
Puranik, Gururaj Venkatesh
Kavishwar, Vikas
author_facet Gupta, Anurag
Dhume, Varsha
Puranik, Gururaj Venkatesh
Kavishwar, Vikas
author_sort Gupta, Anurag
collection PubMed
description BACKGROUND: To utilise an autopsy-based approach to study the febrile deaths and deaths due to malaria during monsoon period of three years at a tertiary care teaching hospital in Mumbai, India. MATERIALS AND METHODS: All autopsies done at the hospital during monsoon period from 2005 to 2007 when fever was the main presenting symptom were included in the study. Monsoon period was defined from June to September. A study on the duration of hospital stay of malaria deaths was also attempted. RESULTS: There were 202 autopsies of febrile illness during the study period. Malaria resulted in 20.8% of the deaths besides other causes. A majority of deaths had intrapulmonary haemorrhages as the only pathological finding. Incidence of malaria deaths was more during monsoon period than the non-monsoon period. Plasmodium falciparum was the most common species responsible for malaria deaths while cerebral malaria was the most common mode of death. In 27% of the cases, post-mortem examination helped to arrive at the correct final diagnosis. In 88.1% of the cases, malaria deaths occurred within the first 24 hours of admission to the hospital. CONCLUSION: The study reiterates the fact that malaria remains a preventable but major cause of death in India, predominantly during the monsoon period. The study also emphasises the importance of developing treatment protocols for malaria during such crucial times besides reinforcing the existing preventive measures.
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spelling pubmed-43148632015-02-05 Autopsy study of febrile deaths during monsoon at a tertiary care institute in India: Is malaria still a challenge? Gupta, Anurag Dhume, Varsha Puranik, Gururaj Venkatesh Kavishwar, Vikas Niger Med J Original Article BACKGROUND: To utilise an autopsy-based approach to study the febrile deaths and deaths due to malaria during monsoon period of three years at a tertiary care teaching hospital in Mumbai, India. MATERIALS AND METHODS: All autopsies done at the hospital during monsoon period from 2005 to 2007 when fever was the main presenting symptom were included in the study. Monsoon period was defined from June to September. A study on the duration of hospital stay of malaria deaths was also attempted. RESULTS: There were 202 autopsies of febrile illness during the study period. Malaria resulted in 20.8% of the deaths besides other causes. A majority of deaths had intrapulmonary haemorrhages as the only pathological finding. Incidence of malaria deaths was more during monsoon period than the non-monsoon period. Plasmodium falciparum was the most common species responsible for malaria deaths while cerebral malaria was the most common mode of death. In 27% of the cases, post-mortem examination helped to arrive at the correct final diagnosis. In 88.1% of the cases, malaria deaths occurred within the first 24 hours of admission to the hospital. CONCLUSION: The study reiterates the fact that malaria remains a preventable but major cause of death in India, predominantly during the monsoon period. The study also emphasises the importance of developing treatment protocols for malaria during such crucial times besides reinforcing the existing preventive measures. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4314863/ /pubmed/25657486 http://dx.doi.org/10.4103/0300-1652.149163 Text en Copyright: © Nigerian Medical Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Gupta, Anurag
Dhume, Varsha
Puranik, Gururaj Venkatesh
Kavishwar, Vikas
Autopsy study of febrile deaths during monsoon at a tertiary care institute in India: Is malaria still a challenge?
title Autopsy study of febrile deaths during monsoon at a tertiary care institute in India: Is malaria still a challenge?
title_full Autopsy study of febrile deaths during monsoon at a tertiary care institute in India: Is malaria still a challenge?
title_fullStr Autopsy study of febrile deaths during monsoon at a tertiary care institute in India: Is malaria still a challenge?
title_full_unstemmed Autopsy study of febrile deaths during monsoon at a tertiary care institute in India: Is malaria still a challenge?
title_short Autopsy study of febrile deaths during monsoon at a tertiary care institute in India: Is malaria still a challenge?
title_sort autopsy study of febrile deaths during monsoon at a tertiary care institute in india: is malaria still a challenge?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314863/
https://www.ncbi.nlm.nih.gov/pubmed/25657486
http://dx.doi.org/10.4103/0300-1652.149163
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