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Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual I(K1)
Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) are widely used in studying basic mechanisms of cardiac arrhythmias that are caused by ion channelopathies. Unfortunately, the action potential profile of hiPSC-CMs—and consequently the profile of individual membrane currents act...
Autores principales: | Meijer van Putten, Rosalie M. E., Mengarelli, Isabella, Guan, Kaomei, Zegers, Jan G., van Ginneken, Antoni C. G., Verkerk, Arie O., Wilders, Ronald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315032/ https://www.ncbi.nlm.nih.gov/pubmed/25691870 http://dx.doi.org/10.3389/fphys.2015.00007 |
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