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Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway

Detalles Bibliográficos
Autores principales: Caporali, Simona, Alvino, Ester, Amaro, Adriana, Lacal, Pedro Miguel, Levati, Lauretta, Atzori, Maria Grazia, Cappellini, Gian Carlo Antonini, Ruffini, Federica, Bonmassar, Enzo, Pfeffer, Ulrich, D’Atri, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315285/
http://dx.doi.org/10.1186/1479-5876-13-S1-P5
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author Caporali, Simona
Alvino, Ester
Amaro, Adriana
Lacal, Pedro Miguel
Levati, Lauretta
Atzori, Maria Grazia
Cappellini, Gian Carlo Antonini
Ruffini, Federica
Bonmassar, Enzo
Pfeffer, Ulrich
D’Atri, Stefania
author_facet Caporali, Simona
Alvino, Ester
Amaro, Adriana
Lacal, Pedro Miguel
Levati, Lauretta
Atzori, Maria Grazia
Cappellini, Gian Carlo Antonini
Ruffini, Federica
Bonmassar, Enzo
Pfeffer, Ulrich
D’Atri, Stefania
author_sort Caporali, Simona
collection PubMed
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spelling pubmed-43152852015-02-12 Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway Caporali, Simona Alvino, Ester Amaro, Adriana Lacal, Pedro Miguel Levati, Lauretta Atzori, Maria Grazia Cappellini, Gian Carlo Antonini Ruffini, Federica Bonmassar, Enzo Pfeffer, Ulrich D’Atri, Stefania J Transl Med Poster Presentation BioMed Central 2015-01-15 /pmc/articles/PMC4315285/ http://dx.doi.org/10.1186/1479-5876-13-S1-P5 Text en Copyright © 2015 Caporali et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Poster Presentation
Caporali, Simona
Alvino, Ester
Amaro, Adriana
Lacal, Pedro Miguel
Levati, Lauretta
Atzori, Maria Grazia
Cappellini, Gian Carlo Antonini
Ruffini, Federica
Bonmassar, Enzo
Pfeffer, Ulrich
D’Atri, Stefania
Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway
title Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway
title_full Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway
title_fullStr Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway
title_full_unstemmed Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway
title_short Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway
title_sort melanoma cells with acquired resistance to dabrafenib display changes in mirna expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of nf-κb or the pi3k/mtor signalling pathway
topic Poster Presentation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315285/
http://dx.doi.org/10.1186/1479-5876-13-S1-P5
work_keys_str_mv AT caporalisimona melanomacellswithacquiredresistancetodabrafenibdisplaychangesinmirnaexpressionpatternandrespondtothisdrugwithanincreaseofinvasivenesswhichisabrogatedbyinhibitionofnfkborthepi3kmtorsignallingpathway
AT alvinoester melanomacellswithacquiredresistancetodabrafenibdisplaychangesinmirnaexpressionpatternandrespondtothisdrugwithanincreaseofinvasivenesswhichisabrogatedbyinhibitionofnfkborthepi3kmtorsignallingpathway
AT amaroadriana melanomacellswithacquiredresistancetodabrafenibdisplaychangesinmirnaexpressionpatternandrespondtothisdrugwithanincreaseofinvasivenesswhichisabrogatedbyinhibitionofnfkborthepi3kmtorsignallingpathway
AT lacalpedromiguel melanomacellswithacquiredresistancetodabrafenibdisplaychangesinmirnaexpressionpatternandrespondtothisdrugwithanincreaseofinvasivenesswhichisabrogatedbyinhibitionofnfkborthepi3kmtorsignallingpathway
AT levatilauretta melanomacellswithacquiredresistancetodabrafenibdisplaychangesinmirnaexpressionpatternandrespondtothisdrugwithanincreaseofinvasivenesswhichisabrogatedbyinhibitionofnfkborthepi3kmtorsignallingpathway
AT atzorimariagrazia melanomacellswithacquiredresistancetodabrafenibdisplaychangesinmirnaexpressionpatternandrespondtothisdrugwithanincreaseofinvasivenesswhichisabrogatedbyinhibitionofnfkborthepi3kmtorsignallingpathway
AT cappellinigiancarloantonini melanomacellswithacquiredresistancetodabrafenibdisplaychangesinmirnaexpressionpatternandrespondtothisdrugwithanincreaseofinvasivenesswhichisabrogatedbyinhibitionofnfkborthepi3kmtorsignallingpathway
AT ruffinifederica melanomacellswithacquiredresistancetodabrafenibdisplaychangesinmirnaexpressionpatternandrespondtothisdrugwithanincreaseofinvasivenesswhichisabrogatedbyinhibitionofnfkborthepi3kmtorsignallingpathway
AT bonmassarenzo melanomacellswithacquiredresistancetodabrafenibdisplaychangesinmirnaexpressionpatternandrespondtothisdrugwithanincreaseofinvasivenesswhichisabrogatedbyinhibitionofnfkborthepi3kmtorsignallingpathway
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AT datristefania melanomacellswithacquiredresistancetodabrafenibdisplaychangesinmirnaexpressionpatternandrespondtothisdrugwithanincreaseofinvasivenesswhichisabrogatedbyinhibitionofnfkborthepi3kmtorsignallingpathway