A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes

Mechanisms to coordinate programs of highly transcribed genes required for cellular homeostasis and growth are unclear. Upstream binding transcription factor (UBTF, also called UBF) is thought to function exclusively in RNA polymerase I (Pol I)-specific transcription of the ribosomal genes. Here, we...

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Detalles Bibliográficos
Autores principales: Sanij, Elaine, Diesch, Jeannine, Lesmana, Analia, Poortinga, Gretchen, Hein, Nadine, Lidgerwood, Grace, Cameron, Donald P., Ellul, Jason, Goodall, Gregory J., Wong, Lee H., Dhillon, Amardeep S., Hamdane, Nourdine, Rothblum, Lawrence I., Pearson, Richard B., Haviv, Izhak, Moss, Tom, Hannan, Ross D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315294/
https://www.ncbi.nlm.nih.gov/pubmed/25452314
http://dx.doi.org/10.1101/gr.176115.114

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