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Genome-wide discovery of human splicing branchpoints
During the splicing reaction, the 5′ intron end is joined to the branchpoint nucleotide, selecting the next exon to incorporate into the mature RNA and forming an intron lariat, which is excised. Despite a critical role in gene splicing, the locations and features of human splicing branchpoints are...
Autores principales: | Mercer, Tim R., Clark, Michael B., Andersen, Stacey B., Brunck, Marion E., Haerty, Wilfried, Crawford, Joanna, Taft, Ryan J., Nielsen, Lars K., Dinger, Marcel E., Mattick, John S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315302/ https://www.ncbi.nlm.nih.gov/pubmed/25561518 http://dx.doi.org/10.1101/gr.182899.114 |
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