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Individualized medicine enabled by genomics in Saudi Arabia
The biomedical research sector in Saudi Arabia has recently received special attention from the government, which is currently supporting research aimed at improving the understanding and treatment of common diseases afflicting Saudi Arabian society. To build capacity for research and training, a nu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315314/ https://www.ncbi.nlm.nih.gov/pubmed/25951871 http://dx.doi.org/10.1186/1755-8794-8-S1-S3 |
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author | Abu-Elmagd, Muhammad Assidi, Mourad Schulten, Hans-Juergen Dallol, Ashraf Pushparaj, Peter Natesan Ahmed, Farid Scherer, Stephen W Al-Qahtani, Mohammed |
author_facet | Abu-Elmagd, Muhammad Assidi, Mourad Schulten, Hans-Juergen Dallol, Ashraf Pushparaj, Peter Natesan Ahmed, Farid Scherer, Stephen W Al-Qahtani, Mohammed |
author_sort | Abu-Elmagd, Muhammad |
collection | PubMed |
description | The biomedical research sector in Saudi Arabia has recently received special attention from the government, which is currently supporting research aimed at improving the understanding and treatment of common diseases afflicting Saudi Arabian society. To build capacity for research and training, a number of centres of excellence were established in different areas of the country. Among these, is the Centre of Excellence in Genomic Medicine Research (CEGMR) at King Abdulaziz University, Jeddah, with its internationally ranked and highly productive team performing translational research in the area of individualized medicine. Here, we present a panorama of the recent trends in different areas of biomedical research in Saudi Arabia drawing from our vision of where genomics will have maximal impact in the Kingdom of Saudi Arabia. We describe advances in a number of research areas including; congenital malformations, infertility, consanguinity and pre-implantation genetic diagnosis, cancer and genomic classifications in Saudi Arabia, epigenetic explanations of idiopathic disease, and pharmacogenomics and personalized medicine. We conclude that CEGMR will continue to play a pivotal role in advances in the field of genomics and research in this area is facing a number of challenges including generating high quality control data from Saudi population and policies for using these data need to comply with the international set up. |
format | Online Article Text |
id | pubmed-4315314 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-43153142015-02-12 Individualized medicine enabled by genomics in Saudi Arabia Abu-Elmagd, Muhammad Assidi, Mourad Schulten, Hans-Juergen Dallol, Ashraf Pushparaj, Peter Natesan Ahmed, Farid Scherer, Stephen W Al-Qahtani, Mohammed BMC Med Genomics Review The biomedical research sector in Saudi Arabia has recently received special attention from the government, which is currently supporting research aimed at improving the understanding and treatment of common diseases afflicting Saudi Arabian society. To build capacity for research and training, a number of centres of excellence were established in different areas of the country. Among these, is the Centre of Excellence in Genomic Medicine Research (CEGMR) at King Abdulaziz University, Jeddah, with its internationally ranked and highly productive team performing translational research in the area of individualized medicine. Here, we present a panorama of the recent trends in different areas of biomedical research in Saudi Arabia drawing from our vision of where genomics will have maximal impact in the Kingdom of Saudi Arabia. We describe advances in a number of research areas including; congenital malformations, infertility, consanguinity and pre-implantation genetic diagnosis, cancer and genomic classifications in Saudi Arabia, epigenetic explanations of idiopathic disease, and pharmacogenomics and personalized medicine. We conclude that CEGMR will continue to play a pivotal role in advances in the field of genomics and research in this area is facing a number of challenges including generating high quality control data from Saudi population and policies for using these data need to comply with the international set up. BioMed Central 2015-01-15 /pmc/articles/PMC4315314/ /pubmed/25951871 http://dx.doi.org/10.1186/1755-8794-8-S1-S3 Text en Copyright © 2015 Abu-Elmagd et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Abu-Elmagd, Muhammad Assidi, Mourad Schulten, Hans-Juergen Dallol, Ashraf Pushparaj, Peter Natesan Ahmed, Farid Scherer, Stephen W Al-Qahtani, Mohammed Individualized medicine enabled by genomics in Saudi Arabia |
title | Individualized medicine enabled by genomics in Saudi Arabia |
title_full | Individualized medicine enabled by genomics in Saudi Arabia |
title_fullStr | Individualized medicine enabled by genomics in Saudi Arabia |
title_full_unstemmed | Individualized medicine enabled by genomics in Saudi Arabia |
title_short | Individualized medicine enabled by genomics in Saudi Arabia |
title_sort | individualized medicine enabled by genomics in saudi arabia |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315314/ https://www.ncbi.nlm.nih.gov/pubmed/25951871 http://dx.doi.org/10.1186/1755-8794-8-S1-S3 |
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