Functional Mapping of the Human Visual Cortex with Intravoxel Incoherent Motion MRI

Functional imaging with intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) is demonstrated. Images were acquired at 3 Tesla using a standard Stejskal-Tanner diffusion-weighted echo-planar imaging sequence with multiple b-values. Cerebro-spinal fluid signal, which is highly incohere...

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Autores principales: Federau, Christian, O’Brien, Kieran, Birbaumer, Adrien, Meuli, Reto, Hagmann, Patric, Maeder, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315413/
https://www.ncbi.nlm.nih.gov/pubmed/25647423
http://dx.doi.org/10.1371/journal.pone.0117706
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author Federau, Christian
O’Brien, Kieran
Birbaumer, Adrien
Meuli, Reto
Hagmann, Patric
Maeder, Philippe
author_facet Federau, Christian
O’Brien, Kieran
Birbaumer, Adrien
Meuli, Reto
Hagmann, Patric
Maeder, Philippe
author_sort Federau, Christian
collection PubMed
description Functional imaging with intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) is demonstrated. Images were acquired at 3 Tesla using a standard Stejskal-Tanner diffusion-weighted echo-planar imaging sequence with multiple b-values. Cerebro-spinal fluid signal, which is highly incoherent, was suppressed with an inversion recovery preparation pulse. IVIM microvascular perfusion parameters were calculated according to a two-compartment (vascular and non-vascular) diffusion model. The results obtained in 8 healthy human volunteers during visual stimulation are presented. The IVIM blood flow related parameter fD* increased 170% during stimulation in the visual cortex, and 70% in the underlying white matter.
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spelling pubmed-43154132015-02-13 Functional Mapping of the Human Visual Cortex with Intravoxel Incoherent Motion MRI Federau, Christian O’Brien, Kieran Birbaumer, Adrien Meuli, Reto Hagmann, Patric Maeder, Philippe PLoS One Research Article Functional imaging with intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) is demonstrated. Images were acquired at 3 Tesla using a standard Stejskal-Tanner diffusion-weighted echo-planar imaging sequence with multiple b-values. Cerebro-spinal fluid signal, which is highly incoherent, was suppressed with an inversion recovery preparation pulse. IVIM microvascular perfusion parameters were calculated according to a two-compartment (vascular and non-vascular) diffusion model. The results obtained in 8 healthy human volunteers during visual stimulation are presented. The IVIM blood flow related parameter fD* increased 170% during stimulation in the visual cortex, and 70% in the underlying white matter. Public Library of Science 2015-02-03 /pmc/articles/PMC4315413/ /pubmed/25647423 http://dx.doi.org/10.1371/journal.pone.0117706 Text en © 2015 Federau et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Federau, Christian
O’Brien, Kieran
Birbaumer, Adrien
Meuli, Reto
Hagmann, Patric
Maeder, Philippe
Functional Mapping of the Human Visual Cortex with Intravoxel Incoherent Motion MRI
title Functional Mapping of the Human Visual Cortex with Intravoxel Incoherent Motion MRI
title_full Functional Mapping of the Human Visual Cortex with Intravoxel Incoherent Motion MRI
title_fullStr Functional Mapping of the Human Visual Cortex with Intravoxel Incoherent Motion MRI
title_full_unstemmed Functional Mapping of the Human Visual Cortex with Intravoxel Incoherent Motion MRI
title_short Functional Mapping of the Human Visual Cortex with Intravoxel Incoherent Motion MRI
title_sort functional mapping of the human visual cortex with intravoxel incoherent motion mri
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315413/
https://www.ncbi.nlm.nih.gov/pubmed/25647423
http://dx.doi.org/10.1371/journal.pone.0117706
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