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Signatures of Natural Selection at the FTO (Fat Mass and Obesity Associated) Locus in Human Populations
BACKGROUND AND AIMS: Polymorphisms in the first intron of FTO have been robustly replicated for associations with obesity. In the Sorbs, a Slavic population resident in Germany, the strongest effect on body mass index (BMI) was found for a variant in the third intron of FTO (rs17818902). Since this...
Autores principales: | Liu, Xuanshi, Weidle, Kerstin, Schröck, Kristin, Tönjes, Anke, Schleinitz, Dorit, Breitfeld, Jana, Stumvoll, Michael, Böttcher, Yvonne, Schöneberg, Torsten, Kovacs, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315420/ https://www.ncbi.nlm.nih.gov/pubmed/25647475 http://dx.doi.org/10.1371/journal.pone.0117093 |
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