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Chronic Bronchitis and Current Smoking Are Associated with More Goblet Cells in Moderate to Severe COPD and Smokers without Airflow Obstruction

BACKGROUND: Goblet cell hyperplasia is a classic but variable pathologic finding in COPD. Current literature shows that smoking is a risk factor for chronic bronchitis but the relationship of these clinical features to the presence and magnitude of large airway goblet cell hyperplasia has not been w...

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Detalles Bibliográficos
Autores principales: Kim, Victor, Oros, Michelle, Durra, Heba, Kelsen, Steven, Aksoy, Mark, Cornwell, William D., Rogers, Thomas J., Criner, Gerard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315442/
https://www.ncbi.nlm.nih.gov/pubmed/25646735
http://dx.doi.org/10.1371/journal.pone.0116108