MIBG scans in patients with stage 4 neuroblastoma reveal two metastatic patterns, one is associated with MYCN amplification and in MYCN-amplified tumours correlates with a better prognosis

PURPOSE: The aim of this study was to find clinically relevant MIBG-avid metastatic patterns in patients with newly diagnosed stage 4 neuroblastoma. METHODS: Diagnostic (123)I-MIBG scans from 249 patients (123 from a European and 126 from the COG cohort) were assessed for metastatic spread in 14 bod...

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Detalles Bibliográficos
Autores principales: Bleeker, Gitta, van Eck-Smit, Berthe L., Zwinderman, Koos H., Versteeg, Rogier, van Noesel, Max M., Kam, Boen L., Kaspers, Gertjan J., van Schie, Annelies, Kreissman, Susan G., Yanik, Gregory, Hero, Barbara, Schmidt, Matthias, Laureys, Geneviève, Lambert, Bieke, Øra, Ingrid, Schulte, Johannes H., Caron, Huib N., Tytgat, Godelieve A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315489/
https://www.ncbi.nlm.nih.gov/pubmed/25267348
http://dx.doi.org/10.1007/s00259-014-2909-1

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