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Comprehensive Evaluation of the Immune Risk Phenotype in Successfully Treated HIV-Infected Individuals

BACKGROUND: Despite successful treatment and CD4+ T-cell recovery, HIV-infected individuals often experience a profound immune dysregulation characterized by a persistently low CD4:CD8 T-cell ratio. This residual immune dysregulation is reminiscent of the Immune Risk Phenotype (IRP) previously assoc...

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Detalles Bibliográficos
Autores principales: Ndumbi, Patricia, Gilbert, Louise, Tsoukas, Christos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315523/
https://www.ncbi.nlm.nih.gov/pubmed/25647167
http://dx.doi.org/10.1371/journal.pone.0117039