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Pre- and Postnatal Risk Factors in Relation to Allergic Rhinitis in School-Aged Children in China
OBJECTIVE: The objective of this study was to investigate the relationship between prenatal and postnatal risk factors and the prevalence of allergic rhinitis (AR) in Chinese children of specific ages. STUDY DESIGN: This study was a cross-sectional survey. Students from 8 metropolitan cities in Chin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315592/ https://www.ncbi.nlm.nih.gov/pubmed/25647669 http://dx.doi.org/10.1371/journal.pone.0114022 |
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author | Li, Youjin Jiang, Yanrui Li, Shenghui Shen, Xiaoming Liu, Jinfen Jiang, Fan |
author_facet | Li, Youjin Jiang, Yanrui Li, Shenghui Shen, Xiaoming Liu, Jinfen Jiang, Fan |
author_sort | Li, Youjin |
collection | PubMed |
description | OBJECTIVE: The objective of this study was to investigate the relationship between prenatal and postnatal risk factors and the prevalence of allergic rhinitis (AR) in Chinese children of specific ages. STUDY DESIGN: This study was a cross-sectional survey. Students from 8 metropolitan cities in China were studied in November and December, 2005. There were 20,803 elementary-school Chinese children (49.6% boys, mean age, 9.19 years) enrolled. Questions from the standard questionnaire of the International Study of Asthma and Allergies in Children were completed to enable us to examine the pattern of current AR. The potential confounders and pre-and postnatal risk factors were analyzed using logistic regression. RESULTS: The overall prevalence of AR was found in this study to be 9.8%. After adjusting for several likely confounders, there was a higher likelihood of AR in school-aged children who were not exclusively breastfed in the first 4 months of their lives (odds ratio [OR]: 1.28; 95% confidence interval [CI]: 1.16–1.41), children who were born post-term (OR: 1.34; 95% CI: 1.12–1.60), children delivered by cesarean section (OR: 1.07; 95% CI: 1.00–1.19), or children born to mothers who experienced depressive symptoms during the pre- and postnatal periods (OR: 1.28; 95% CI: 1.15–1.42). CONCLUSIONS: AR in school-aged children was found to be associated with pre- and postnatal events. These findings indicate that strategies to reduce exposure to risk factors during pre- and postnatal periods for childhood allergies might be warranted. |
format | Online Article Text |
id | pubmed-4315592 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-43155922015-02-13 Pre- and Postnatal Risk Factors in Relation to Allergic Rhinitis in School-Aged Children in China Li, Youjin Jiang, Yanrui Li, Shenghui Shen, Xiaoming Liu, Jinfen Jiang, Fan PLoS One Research Article OBJECTIVE: The objective of this study was to investigate the relationship between prenatal and postnatal risk factors and the prevalence of allergic rhinitis (AR) in Chinese children of specific ages. STUDY DESIGN: This study was a cross-sectional survey. Students from 8 metropolitan cities in China were studied in November and December, 2005. There were 20,803 elementary-school Chinese children (49.6% boys, mean age, 9.19 years) enrolled. Questions from the standard questionnaire of the International Study of Asthma and Allergies in Children were completed to enable us to examine the pattern of current AR. The potential confounders and pre-and postnatal risk factors were analyzed using logistic regression. RESULTS: The overall prevalence of AR was found in this study to be 9.8%. After adjusting for several likely confounders, there was a higher likelihood of AR in school-aged children who were not exclusively breastfed in the first 4 months of their lives (odds ratio [OR]: 1.28; 95% confidence interval [CI]: 1.16–1.41), children who were born post-term (OR: 1.34; 95% CI: 1.12–1.60), children delivered by cesarean section (OR: 1.07; 95% CI: 1.00–1.19), or children born to mothers who experienced depressive symptoms during the pre- and postnatal periods (OR: 1.28; 95% CI: 1.15–1.42). CONCLUSIONS: AR in school-aged children was found to be associated with pre- and postnatal events. These findings indicate that strategies to reduce exposure to risk factors during pre- and postnatal periods for childhood allergies might be warranted. Public Library of Science 2015-02-03 /pmc/articles/PMC4315592/ /pubmed/25647669 http://dx.doi.org/10.1371/journal.pone.0114022 Text en © 2015 Li et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Li, Youjin Jiang, Yanrui Li, Shenghui Shen, Xiaoming Liu, Jinfen Jiang, Fan Pre- and Postnatal Risk Factors in Relation to Allergic Rhinitis in School-Aged Children in China |
title | Pre- and Postnatal Risk Factors in Relation to Allergic Rhinitis in School-Aged Children in China |
title_full | Pre- and Postnatal Risk Factors in Relation to Allergic Rhinitis in School-Aged Children in China |
title_fullStr | Pre- and Postnatal Risk Factors in Relation to Allergic Rhinitis in School-Aged Children in China |
title_full_unstemmed | Pre- and Postnatal Risk Factors in Relation to Allergic Rhinitis in School-Aged Children in China |
title_short | Pre- and Postnatal Risk Factors in Relation to Allergic Rhinitis in School-Aged Children in China |
title_sort | pre- and postnatal risk factors in relation to allergic rhinitis in school-aged children in china |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315592/ https://www.ncbi.nlm.nih.gov/pubmed/25647669 http://dx.doi.org/10.1371/journal.pone.0114022 |
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