Cargando…
Primary Biliary Acids Inhibit Hepatitis D Virus (HDV) Entry into Human Hepatoma Cells Expressing the Sodium-Taurocholate Cotransporting Polypeptide (NTCP)
BACKGROUND: The sodium-taurocholate cotransporting polypeptide (NTCP) is both a key bile acid (BA) transporter mediating uptake of BA into hepatocytes and an essential receptor for hepatitis B virus (HBV) and hepatitis D virus (HDV). In this study we aimed to characterize to what extent and through...
Autores principales: | Veloso Alves Pereira, Isabel, Buchmann, Bettina, Sandmann, Lisa, Sprinzl, Kathrin, Schlaphoff, Verena, Döhner, Katinka, Vondran, Florian, Sarrazin, Christoph, Manns, Michael P., Pinto Marques Souza de Oliveira, Cláudia, Sodeik, Beate, Ciesek, Sandra, von Hahn, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315608/ https://www.ncbi.nlm.nih.gov/pubmed/25646622 http://dx.doi.org/10.1371/journal.pone.0117152 |
Ejemplares similares
-
Effect of mTOR inhibitors on sodium taurocholate cotransporting polypeptide (NTCP) function in vitro
por: Saran, Chitra, et al.
Publicado: (2023) -
Structural Plasticity Is a Feature of Rheostat Positions in the Human Na(+)/Taurocholate Cotransporting Polypeptide (NTCP)
por: Ruggiero, Melissa J., et al.
Publicado: (2022) -
A clinically relevant polymorphism in the Na(+)/taurocholate cotransporting polypeptide (NTCP) occurs at a rheostat position
por: Ruggiero, Melissa J., et al.
Publicado: (2020) -
The Lipid Raft Component Stomatin Interacts with the Na(+) Taurocholate Cotransporting Polypeptide (NTCP) and Modulates Bile Salt Uptake
por: Appelman, Monique D., et al.
Publicado: (2020) -
N-Glycosylation of the Na+-Taurocholate Cotransporting Polypeptide (NTCP) Determines Its Trafficking and Stability and Is Required for Hepatitis B Virus Infection
por: Appelman, Monique D., et al.
Publicado: (2017)