Pichia pastoris secretes recombinant proteins less efficiently than Chinese hamster ovary cells but allows higher space-time yields for less complex proteins

Chinese hamster ovary (CHO) cells are currently the workhorse of the biopharmaceutical industry. However, yeasts such as Pichia pastoris are about to enter this field. To compare their capability for recombinant protein secretion, P. pastoris strains and CHO cell lines producing human serum albumin...

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Detalles Bibliográficos
Autores principales: Maccani, Andreas, Landes, Nils, Stadlmayr, Gerhard, Maresch, Daniel, Leitner, Christian, Maurer, Michael, Gasser, Brigitte, Ernst, Wolfgang, Kunert, Renate, Mattanovich, Diethard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315903/
https://www.ncbi.nlm.nih.gov/pubmed/24390926
http://dx.doi.org/10.1002/biot.201300305

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