Cargando…
Batf3-dependent CD103(+) dendritic cells are major producers of IL-12 that drive local Th1 immunity against Leishmania major infection in mice
The role of different DC subsets in priming and maintenance of immunity against Leishmania major (L. major) infection is debated. The transcription factor basic leucine zipper transcription factor, ATF-like 3 (Batf3) is essential for the development of mouse CD103(+) DCs and some functions of CD8α(+...
Autores principales: | Martínez-López, María, Iborra, Salvador, Conde-Garrosa, Ruth, Sancho, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316187/ https://www.ncbi.nlm.nih.gov/pubmed/25312824 http://dx.doi.org/10.1002/eji.201444651 |
Ejemplares similares
-
l-Arginine deprivation impairs Leishmania major-specific T-cell responses
por: Munder, Markus, et al.
Publicado: (2009) -
IL-18, but not IL-15, contributes to the IL-12-dependent induction of NK-cell effector functions by Leishmania infantum in vivo
por: Haeberlein, Simone, et al.
Publicado: (2010) -
Type I IFN signaling facilitates the development of IL‐10‐producing effector CD8(+) T cells during murine influenza virus infection
por: Jiang, Li, et al.
Publicado: (2016) -
Soluble flagellin coimmunization attenuates Th1 priming to Salmonella and clearance by modulating dendritic cell activation and cytokine production
por: Flores‐Langarica, Adriana, et al.
Publicado: (2015) -
Epstein–Barr virus and malaria upregulate AID and APOBEC3 enzymes, but only AID seems to play a major mutagenic role in Burkitt lymphoma
por: Summerauer, Andrea M., et al.
Publicado: (2022)