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A novel artificial nerve graft for repairing long-distance sciatic nerve defects: a self-assembling peptide nanofiber scaffold-containing poly(lactic-co-glycolic acid) conduit

In this study, we developed a novel artificial nerve graft termed self-assembling peptide nanofiber scaffold (SAPNS)-containing poly(lactic-co-glycolic acid) (PLGA) conduit (SPC) and used it to bridge a 10-mm-long sciatic nerve defect in the rat. Retrograde tracing, behavioral testing and histomorph...

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Detalles Bibliográficos
Autores principales: Wang, Xianghai, Pan, Mengjie, Wen, Jinkun, Tang, Yinjuan, Hamilton, Audra D., Li, Yuanyuan, Qian, Changhui, Liu, Zhongying, Wu, Wutian, Guo, Jiasong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316446/
https://www.ncbi.nlm.nih.gov/pubmed/25657734
http://dx.doi.org/10.4103/1673-5374.147944